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Steatosis shapes prognosis-defining liver metastasis heterogeneity in CRC - Nature
Liver steatosis increases formation of replacement liver metastases by increasing MYC stability through acetylation, which increases proline synthesis and collagen production.
Bending Spoons defies SaaS slump, surges 40% on first day of trading - TechCrunch
The company has grown rapidly by acquiring and revamping last-generation tech brands like AOL, Eventbrite, Evernote, Meetup, and Vimeo.
‘X-Men ’97’ Creator Beau DeMayo Claims He Was “Very Honest” With Marvel About OnlyFans Work, Felt Like “DEI Hire” - Deadline
Nearly two years after suing Marvel, Beau DeMayo has opened up about the alleged treatment he endured leading up to his March 2024 termination.
A secreted endosymbiont protein essential for colonizing host cells - Nature
SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of bacterial pathogens and is essential for Buchnera transmission.
Heat-triggered phospholipid flipping stabilizes plasma membrane fluidity - Nature
In rice, the P4-ATPase complex OsALA5–OsALIS2 rapidly stabilizes membrane fluidity in response to high temperature by flipping saturated phosphatidylcholines to the cytosolic leaflet of the plasma membrane.
Restoring cortical disinhibition improves Huntington’s disease phenotypes - Nature
In a mouse model of Huntington’s disease, targeted modulation of neuronal activity restores network function and improves motor deficits.