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Genome modelling and design across all domains of life with Evo 2 - Nature
Evo 2 is an artificial intelligence-based biological foundation model trained on 9 trillion DNA base pairs spanning all domains of life that predicts functional properties from genomic sequences and provides a rich generative model for researchers in biology.
Mechanism of co-transcriptional cap snatching by influenza polymerase - Nature
Structural and biochemical studies of influenza virus RNA-dependent RNA polymerase (FluPol) in complex with transcribing host RNA polymerase II reveal the molecular mechanisms of RNA cap snatching by FluPol.
The molecular basis of force selectivity by PIEZO2 - Nature
PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.
Microbiota-mediated induction of beige adipocytes in response to dietary cues - Nature
In mice, a low-protein diet leads to a gut-microbiota-driven remodelling of adipose tissue towards brown fat, showing that gut microorganisms have a role in detecting and responding to a lack of protein.
Netflix, After Walking Away From Warner Bros. Deal, Will 'Move Forward' With '$2.8 Billion in Our Pocket That We Didn't Have a Few Weeks Ago,' CFO Says - Variety
Netflix CFO Spence Neumann, speaking Wednesday at the Morgan Stanley Technology, Media & Telecom Conference, reiterated the company’s position that it bailed out of the bidding for Warner Bros. because Paramount increased its offer price.
WWE ‘pleasantly surprised’ by all the human monies Danhausen is making them already - Cageside Seats
His debut was a roller coaster, but the very nice, very evil wrestler is apparently raking it in for his new bosses.