Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor - Nature
health 2026/03/11 22:15:15

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor - Nature

Source:Nature.com
Author:None

Marburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus glycoprotein, accompanied by fusion-relevant rearrangements, enabling more efficient viral entry.